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@article{Alton2015,
 author = {Alton, Eric W F W and Armstrong, David K. and Ashby, Deborah and Bayfield, Katie J. and Bilton, Diana and Bloomfield, Emily V. and Boyd, A. Christopher and Brand, June and Buchan, Ruaridh and Calcedo, Roberto and Carvelli, Paula and Chan, Mario and Cheng, Seng H. and Collie, D. David S. and Cunningham, Steve and Davidson, Heather E. and Davies, Gwyneth and Davies, Jane C. and Davies, Lee A. and Dewar, Maria H. and Doherty, Ann and Donovan, Jackie and Dwyer, Natalie S. and Elgmati, Hala I. and Featherstone, Rosanna F. and Gavino, Jemyr and Gea-Sorli, Sabrina and Geddes, Duncan M. and Gibson, James S. R. and Gill, Deborah R. and Greening, Andrew P. and Griesenbach, Uta and Hansell, David M. and Harman, Katharine and Higgins, Tracy E. and Hodges, Samantha L. and Hyde, Stephen C. and Hyndman, Laura and Innes, J. Alastair and Jacob, Joseph and Jones, Nancy and Keogh, Brian F. and Limberis, Maria P. and Lloyd-Evans, Paul and Maclean, Alan W. and Manvell, Michelle C. and McCormick, Dominique and McGovern, Michael and McLachlan, Gerry and Meng, Cuixiang and Montero, M. Angeles and Milligan, Hazel and Moyce, Laura J. and Murray, Gordon D. and Nicholson, Andrew G. and Osadolor, Tina and Parra-Leiton, Javier and Porteous, David J. and Pringle, Ian A. and Punch, Emma K. and Pytel, Kamila M. and Quittner, Alexandra L. and Rivellini, Gina and Saunders, Clare J. and Scheule, Ronald K. and Sheard, Sarah and Simmonds, Nicholas J. and Smith, Keith and Smith, Stephen N. and Soussi, Najwa and Soussi, Samia and Spearing, Emma J. and Stevenson, Barbara J. and Sumner-Jones, Stephanie G. and Turkkila, Minna and Ureta, Rosa P. and Waller, Michael D. and Wasowicz, Marguerite Y. and Wilson, James M. and Wolstenholme-Hogg, Paul},
 year = {2015},
 title = {Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: A randomised, double-blind, placebo-controlled, phase 2b trial},
 pages = {684--691},
 volume = {3},
 number = {9},
 issn = {22132600},
 journal = {The Lancet Respiratory Medicine},
 doi = {10.1016/S2213-2600(15)00245-3}
}


@article{Somaraju2014,
 author = {Somaraju, Usha Rani and Solis-Moya, Arturo},
 year = {2014},
 title = {Pancreatic enzyme replacement therapy for people with cystic fibrosis},
 pages = {1--53},
 number = {10},
 journal = {The Cochrane Library},
 doi = {10.1002/14651858.CD008227.pub2}
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@article{Sioud2003,
 author = {Sioud, Mouldy and Soerensen, Dag R.},
 year = {2003},
 title = {Cationic liposome-mediated delivery of siRNAs in adult mice},
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 volume = {312},
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 year = {2011},
 title = {The cystic fibrosis transmembrane conductance regulator (CFTR): three-dimensional structure and localization of a channel gate},
 keywords = {Adenosine Triphosphate/chemistry;Biological Transport;Cell Membrane/metabolism;Chromatography, Affinity/methods;Crystallization;Crystallography, X-Ray/methods;Cystic Fibrosis Transmembrane Conductance Regulator/chemistry/genetics;Humans;Ions/chemistry;Microscopy, Electron/methods;Models, Molecular;Molecular Conformation;Phosphorylation;Protein Conformation;Protein Structure, Secondary;Protein Structure, Tertiary;Proteins/chemistry},
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 volume = {286},
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 issn = {1083-351X},
 journal = {The Journal of biological chemistry},
 doi = {10.1074/jbc.M111.292268}
}


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 author = {Raskin, Philip},
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 title = {Bronchospasm after Inhalation of Pancreatic Dornase},
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@article{Odolczyk-2014,
 author = {Odolczyk, Norbert and Zielenkiewicz, Piotr},
 year = {2014},
 title = {Molecular modelling approaches for cystic fibrosis transmembrane conductance regulator studies},
 keywords = {Animals;CFTR;cystic fibrosis;Cystic Fibrosis Transmembrane Conductance Regulator/chemistry/genetics/metabolism;Cystic Fibrosis/genetics/metabolism;Humans;In silico studies;Models, Molecular;Molecular modelling},
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 title = {Engineered ribozymes as molecular tools for site-specific alteration of RNA sequence},
 keywords = {Animals;Base Sequence;DNA Repair;Gene Transfer Techniques;Genetic Therapy/methods;Humans;Introns;Lac Operon;Molecular Sequence Data;Nucleic Acid Conformation;Oligonucleotides/chemistry/metabolism;RNA, Catalytic/biosynthesis/genetics/therapeutic use;Trans-Splicing},
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 title = {A therapeutic regimen for patients with cystic fibrosis},
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 year = {2014},
 title = {Longevity of patients with cystic fibrosis in 2000 to 2010 and beyond: survival analysis of the Cystic Fibrosis Foundation patient registry},
 pages = {233--241},
 volume = {161},
 number = {4},
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 title = {A Phase I Study of Aerosolized Administration of tgAAVCF to Cystic Fibrosis Subjects with Mild Lung Disease},
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@misc{WHO-2004,
 author = {World Health Organisation},
 title = {The molecular genetic epidomology of cystic fibrosis},
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 year = {2010},
 title = {Dornase alfa for cystic fibrosis},
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 journal = {The Cochrane Library}
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@article{Haack2013,
 author = {Haack, Adriana and Aragao, Giselle Goncalves and Noveas, Maria Rita Carvalho Garbi},
 year = {2013},
 title = {Pathophysiology of cystic fibrosis and drugs used in associated digestive tract diseases},
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@article{Gibson1959,
 author = {Gibson, Lewis E. and Cooke, Robert, E.},
 year = {1959},
 title = {A test for concentration of electrolytes in sweat in cystic fibrosis of the pancreas utilizing pilocarpine by ionotophoresis},
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@article{Fuller2000,
 author = {Fuller, W. and Cuthbert, Alan W.},
 year = {2000},
 title = {Post-translational Disruption of the Delta F508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Molecular Chaperone Complex with Geldanamycin Stabilizes Delta F508 CFTR in the Rabbit Reticulocyte Lysate},
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@article{Cutting-2015,
 author = {Cutting, Garry R.},
 year = {2015},
 title = {Cystic fibrosis genetics: from molecular understanding to clinical application},
 keywords = {Cystic Fibrosis Transmembrane Conductance Regulator/genetics;Cystic Fibrosis/genetics/physiopathology;Genetic Therapy/methods;Genetic Variation;Genetics, Medical/methods/trends;Humans;Models, Biological;Molecular Diagnostic Techniques/methods;Phenotype},
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 year = {1994},
 title = {Administration of an adenovirus containing the human CFTR cDNA~to the respiratory tract of individuals with cystic fibrosis},
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 number = {8},
 journal = {Nature Genetics}
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 author = {{Charles A. Mack} and {Wen-Ru Song} and {Heather Carpenter} and {Tom J. Wickham} and {Imre Kovesdi} and {Ben-Gary Harvey} and {Christopher J. Magovern} and {O. Wayne Isom} and {Todd Rosengart} and {Eric Falck-Pedersen} and {Neil R. Hackett} and {Ronald G. Crystal} and {and Andrea Mastrangeli}},
 year = {1997},
 title = {Circumvention of Anti-Adenovirus Neutralizing Immunity by Administration of an Adenoviral Vector of an Alternate Serotype},
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 number = {8},
 journal = {Human Gene Therapy}
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@article{Balke2014,
 author = {Balke, Darko and Zieten, Irene and Strahl, Anne and Mueller, Oliver and Mueller, Sabine},
 year = {2014},
 title = {Design and characterization of a twin ribozyme for potential repair of a deletion mutation within the oncogenic CTNNB1-\textgreek{D}S45 mRNA},
 keywords = {Base Sequence;beta Catenin/drug effects/genetics;DNA Repair/drug effects;Drug Design;Gene Deletion;Kinetics;Molecular Sequence Data;Mutation/drug effects;RNA Cleavage/drug effects;RNA, Catalytic/chemical synthesis/pharmacology;RNA, Messenger/drug effects},
 pages = {2128--2137},
 volume = {9},
 number = {9},
 issn = {1860-7187},
 journal = {ChemMedChem},
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@article{Andersen-1958,
 author = {Andersen, Dorothy H.},
 year = {1958},
 title = {Cystic fibrosis of the pancreas},
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@article{Amaral-2015,
 author = {Amaral, M. D.},
 year = {2015},
 title = {Novel personalized therapies for cystic fibrosis: treating the basic defect in all patients},
 keywords = {Aminoglycosides/therapeutic use;Aminophenols/therapeutic use;Anti-Bacterial Agents/therapeutic use;Anti-Inflammatory Agents/therapeutic use;Biological Markers/blood;Codon, Nonsense;Cystic Fibrosis Transmembrane Conductance Regulator/genetics;Cystic Fibrosis/blood/diagnosis/drug therapy/genetics/mortality;Evidence-Based Medicine;Frameshift Mutation;Genistein/therapeutic use;Humans;Individualized Medicine;Oxadiazoles/therapeutic use;Phenotype;Purinergic Antagonists/therapeutic use;Quinolones/therapeutic use;Rare Diseases;Severity of Illness Index;Sweat Glands/drug effects},
 pages = {155--166},
 volume = {277},
 number = {2},
 issn = {1365-2796},
 journal = {Journal of internal medicine},
 doi = {10.1111/joim.12314}
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 year = {1999},
 title = {A Phase I Study of Adenovirus-Mediated Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator Gene to a Lung Segment of Individuals with Cystic Fibrosis},
 pages = {2973--2985},
 number = {10},
 journal = {Human Gene Therapy}
}


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 author = {Yankaskas, James R. and Mallory, George B. and The Consensus Committee},
 year = {1998},
 title = {Lung transplantation in cystic fibrosis},
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 journal = {Chest}
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